Pellets are made under strict guidelines by a compounding pharmacy. These pellets are the size of a grain of rice. 3-4 mm in diameter. The pellets are placed in the fatty layer under the skin of the buttock. Pellets release steady amounts of hormones. This avoids the up and down problems associated with injection treatment. Pellets can last anywhere from 4-6 months, usually.
Bioidentical hormone replacement therapy (BHRT) or natural hormone therapy basically means that hormones are molecularly identical to your own natural hormones. The pellets are made from wild yams and soy. There are no known allergens associated with wild yams and soy. (Once the hormone is made, it is no longer yam or soy.) Bioidentical hormones have similar risks to conventional hormones. We use a national compounding pharmacy to provide the safest hormones possible. The pharmacy’s quality standards already surpassed what was required by USP 797. They meet the gold standard in the industry for pellets: compliance with the FDA’s standards for CGMP (current good manufacturing practices), the same as large commercial drug manufacturers.
Hormone pellets have advantages compared to other means of replacement. There is no risk of transference, which can happen with gels and creams. Unlike shots, pellets maintain a steady level of hormone levels in the body. Having peaks and valleys with shots create some risk for side-effects.
Peaks can cause the red blood cell counts to go up. Increased blood counts can increase your blood thickness and lead to more cardiac risk. The increase in blood count may require blood donations. Without the high spikes, pellets may reduce the risk of this problem.
Valleys can cause people to feel the problems that led them to hormones in the first place. We do not want your testosterone levels to look like a roller coaster ride.
Finally, with injections, there is need to repeatedly inject. A big advantage of pellets is that they can last for months, which means less trips to the doctor’s office.
The pellets are placed in the fat under the skin of the hip. A tiny opening is made in the skin and the pellets are inserted. No stitch is required. The procedure can be done in the office. We use numbing medication to make the procedure as comfortable as possible.
Pellets can:
This depends. We estimate every 4 to 6 months. We check labs and your symptoms quarterly.
Pellets must be implanted. There is a very low risk of infection. Dosing cannot be decreased once the pellets are implanted. We usually start with a lower dose to avoid issues and calculate future dosing.
For men, testosterone pellets have some of the same risks as other means of testosterone supplementation. External testosterone reduces your own body’s ability to make testosterone. Men who are considering children should not take external testosterone. The risk of increasing your red blood cell count should be decreased.
For women, hormone pellets are not yet FDA-approved. Women have been treated with hormones for years. Reports have shown improvements in sexual desire and satisfaction. There is improvement in bone density, mental sharpness and performance. Risks include lack of longterm studies. There can be some unwanted hair growth and acne with hormone replacement.
Pellets have been shown to be effective for relief of menopause symptoms. They can help decrease loss of bone density. Sexual desire and satisfaction can improve in women with hormone pellets. Similar to men, women can have decreased depression, increased energy and performance with pellet hormone therapy. Vaginal dryness, urinary urgency and frequency can improve with pellet hormone therapy. Studies with cancer risk are ongoing and encouraging. Pellets for women are not FDA approved. However, we can help you understand if your clinical symptoms may benefit from hormonal pellet therapy. Call us or fill in the form for a consultation.
Dr Hlavinka is a urologist with over 20 years of experience. He has a particular interest in women’s sexual medicine. He is a fellow of the International Society for the Study of Women’s Sexual Health. He is the only fellow in all of Texas. Considered the doctor’s doctor for hormone therapy, Dr Hlavinka is South Texas’s go-to expert for hormonal replacement therapy.